SALIVA TESTING

Saliva testing is used for measuring hormones like cortisol, estrogen and testosterone, and its non-invasive collection asks patients to spit into a plastic tube. This sampling method allows patients to collect saliva at home at specific times, which is important for accurately measuring hormone levels.

Why do we test hormones in saliva? Steroid hormones in the bloodstream are 95-99% bound to carrier proteins, and in this form are unavailable to target tissues. Saliva testing measures the amount of hormone available to target tissues – the bioavailable amount. For this reason, saliva testing better relates to specific symptoms of excess or deficiency, and is a good option for monitoring hormone therapy.

ZRT is one of the first labs to measure hormones in saliva, and helped establish the method that made saliva hormone testing commercially viable for health care providers and patients around the globe.

 

Best Practices for Saliva Testing

ZRT measures hormones from a single morning sample, which represents the peak of daily hormone production – the optimal time to measure

Best Practices for Saliva Testing

ZRT measures hormones from a single morning sample, which represents the peak of daily hormone production – the optimal time to measure

Today’s Most Advanced Saliva Testing
Ranges Adjusted for Supplementation
Ranges Adjusted for Supplementation:
Unlike other labs, patients do not need to stop hormone supplementation to use ZRT’s testing because we have ranges adjusted for age, menstrual status and supplementation types. This is the ideal method for tracking the effectiveness of hormone treatments.
No Pooling
No Pooling:
ZRT does not pool patient samples, meaning that we don’t mix multiple daily samples together to get an average hormone level. Instead we measure hormones from a single morning sample, which represents the peak of daily hormone production – the optimal time to measure.
Extraction
Extraction:
ZRT is the only lab to perform an extraction process for saliva testing, which separates hormones from background contamination. This is the only way to assure accurate test results for low-concentration hormones such as estradiol.
Industry Standards
Setting Industry Standards:
ZRT initiated and manages the industry-wide standards program called the Saliva Proficiency Inter-laboratory Testing Program – which enables laboratories to regularly evaluate and improve saliva testing accuracy.
Learn More About Saliva Testing

 

 

HORMONE TESTING FOR DIFFERENT SUPPLEMENTATION TYPES

 

Webinar: Pros & Cons of Testing Steroid Hormones in Saliva

Paper: Saliva Validity

See the Profiles
Hormone Profiles

Saliva Profile I – E2, Pg, T, DS & Cx1

Saliva Profile II – E2, Pg, T, DS & Cx2

Saliva Profile III – E2, Pg, T, DS & Cx4 (Sample Report)

Female Combo Profile I – E2, Pg, T, DS, Cx4 (saliva); TSH, fT3, fT4, TPOab (blood spot) (Sample Report)

Female Como Profile II – Cx4 (saliva); E2, Pg, T, SHBG, DS, TSH, fT3, fT4, TPOab (blood spot) (Sample Report)

Male Combo Profile I – E2, T, DS, Cx4 (saliva); PSA, TSH, fT3, fT4, TPOab (blood spot) (Sample Report)

Male Combo Profile II – Cx4 (saliva); E2, T, DS, SHBG, PSA, TSH, fT3, fT4, TPOab (blood spot) (Sample Report)

Specialty Profiles

Diurnal Cortisol – Cx4

Adrenal Stress Profile – DS & Cx4 (Sample Report)

Cortisol Awakening Response Profile (CAR) - Cx6 (Learn More)

Fertility Profile – Cx4 (saliva); E2, Pg, T, DS, SHBG, TSH, fT3, fT4, TPOab, LH, FSH (blood spot) (Sample Report)

Skin Vitality Profile – E2, E3, Pg, T, DS, Cx4 (saliva); TSH, Vitamin D (blood spot) (Sample Report)

Weight Management Profile – E2, Pg, T, DS, Cx4 (saliva); TSH, Insulin, HbA1c, Vitamin D (blood spot) (Sample Report)

  • With Thyroid add-ons – fT3, fT4, TPOab
  • With Cardio add-ons – hsCRP, TG, CH, LDL, HDL, VLDL

NeuroAdvanced Profile – GABA, Glu, Gly, DA, Epi, NE, HIST, 5-HT, PEA, DOPAC, HVA, 5-HIAA, NMN, VMA (Sample Report)

Saliva Hormones add-on – E2, Pg, T, DS, C

Urine Hormones add-on – E2, Pregnanediol, Allopregnanolone, Androstenedione, T, Epi-T, DHT, DHEA, 5α,3α-Androstanediol

Diurnal Cortisol add-on – Free Cortisol x 4, Free Cortisone x 4

Diurnal Cortisol & Melatonin add-on – Free Cortisol x 4, Free Cortisone x 4, Melatonin (MT6s) x 4

Diurnal Cortisol, Norepinephrine & Epinephrine add-on – Free Cortisol x 4, Free Cortisone x 4, NE x 4, Epi x 4

Diurnal Cortisol, Melatonin, Norepinephrine & Epinephrine add-on – Free Cortisol x 4, Free Cortisone x 4, Melatonin (MT6s) x 4, NE x 4, Epi x 4

Cortisol Awakening Response Profile (CAR) - Cx6 (Learn More)

Reference Information

ZRT Overview of Profiles

ZRT Test Directory & Abbreviations

FAQs

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